Content (Syllabus outline)

• Antimicrobials and antimicrobial resistance mechanisms;

• the problem of resistant bacteria in medicine, veterinary medicine, sewage treatment plants and in particular agriculture;

• searching for alternative antimicrobials;

• selected chapters from microbial eukaryotic genetics;

 

• Stochasticity/bistability of gene expression within genetically uniform bacterial populations;

• biofilms: structure, gene regulation function, antimicrobial resistance;

• micorbial cell-cell signaling: molecular signatures, regulation and responses,

• antibiotics as signaling molecules;

microbial interactions as inducers of antimicrobials and other biologically active compounds;

• social evolution of microorganisms;

• regulation and mechanisms of bacterial movement on surfaces.

 

• Regulation of global microbial responses – regulatory networks;

• responses to stress, virulence, stringent response, synthesis of ribosomes; second messengers

• mechanisms regulating horizontal gene transfer, CRISPR and gene editing; 

• bacterial protein secretion systems;

• bacterial genome plasticity;

• microbial genomics.

Prerequisites

Prerequisites for course work:

• inscription  to adequate academic year  of study programme Microbiology, Msc study

• knowledge of: molecular biology, microbial genetics and microbial physiology

 

Prerequisites for admittance to final exam:

Practical examination (colloquium):

• presence at practicals

Exam:

• practical examination (colloquium)

• seminar presentation