Content (Syllabus outline)
The anatomical and physiological characteristics of laboratory animals. Reproduction, regulation of sexual cycle, superovulation, embryo manipulation and technique of embryo transfer. Nutrition and adaptation of nutrition for different Assessment and levels of production. Schemes of crossbreeding, strategy for development of inbreeding strains, backcrossing and generation of congenic strains. Regulation and management of laboratory and experimental animals breeding colonies, technological and legal norms, different systems of breeding, fulfilling the zoohygiene demand, circulation with laboratory animals, quarantine. Breeding of gnotobiotic and SPF animals. Evidence and indication of animals, computer tools for experimental animal colony management. Review of the most applicable lines and strains of laboratory animals, animal models for the study of some physiological and disease conditions, preparation of gene modification animal models and animals with equal genes. Legislation regulating the breeding of laboratory animals and application or use in experiments. The application procedure and reasoning the use of animals in an experiment, ethical aspects in connection with experimental work on animals, possibilities of a reduction in animal experiments (RRR) and good laboratory practice (GLP).
Requirements for enrolment:
Current’s year enrolment in study programme
Terms of Prerequisites:
Attending course exercises