Content (Syllabus outline)

The importance of homologous recombination for targeted intervention in the genome, knock-out technology, constitutive and conditional knock out technology, production of molecular markers and their application to gene. mapping. Techniques and potential uses of animal cloning. Development of totipotent cell lines, embryonic stem cell technology and production of chimeras. Breeding  strategies for transgenic animals and animals with abolished genes. Biotechnological manipulation of the digestive tract microflora. In vitro expression systems. Transgenic animals for studies of resistance, as models for studying diseases and therapeutic options (xenotransplantation). "Gene pharming" and applications in the pharmaceutical industry. Transgenesis in animal production. Animal models for studying host-pathogen interactions. QTL – concept and applications, the concept of candidate genes, association studies and physical cloning of candidate regions from the animal genome. Biotechnology of the mammary gland.

Prerequisites

Prerequisites for the inclusion in the work:

Enrolment in the corresponding year of study programme.

Prerequisites for performing study obligations:
 - For colloquium: attending tutorials
 - For exam: presentation of seminar paper