Content (Syllabus outline)
-Introduction: history of genetics,design of (genetic) experiment, hypothesis testing
-DNA structure and replication: DNA elements, mechanism of replication
-Transcription and translation: Gene structure, transcription to RNA and translation to protein, regulation of gene expression
-Genes as the unit of inheritance: dominance, recesiveness, penetrance, expressivity
-Mendelian modes of inheritance, qualitative traits, genetic markers, non-Mendelian inheritance
-Chromosomal “theory”, cytogenetics, chromatin structure, karyotype, techniques as FISH, GISH...
-Gene interactions: complementation, pleiotropy, epistasis.
-Linkage and mapping: Meiosis and genetic recombination, genetic linkage analysis
-Genetic markers in animal breeding; types of markers and case of use in animal breeding
-Systems of crosses in animals: experimental crosses, basic crossing schemes used in breeding domestic animal species .
-Bioethics: ethical aspects of animal breeding and animal biotechnology
-Seminar project and presentation: written and oral presentation of a selected scientific original article from the field of animal genetics – a gene that follows simple Mendelian inheritance
Prerequisites
a) Prerequisites for the inclusion in the work:
Enrolment in the corresponding year of study programme and completed exams: Mathematics, Chemistry with Biochemistry and Biology of domestic animals.
b) Prerequisites for performing study obligations:
Prerequisites for the final exam: completed all obligations in the programme of lectures, seminars and laboratory work.